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Histamine and heparan sulfate arevasoactive agents that among other actions cause dilationof small blood vessels. These agentswork in a very similar fashion as sulfonylureas

These agentswork in a very similar fashion as sulfonylureas. Con-sequently, cerebral VSP may not be differentiated from cerebral hyperemia by the mereassessment of FV in the basal arteries (27,28)

Con-sequently, cerebral VSP may not be differentiated from cerebral hyperemia by the mereassessment of FV in the basal arteries (27,28).

Although there wasno difference in mortality in any of these trials,the administration of multiple doses of a naturalsurfactant was found to improve oxygenation inall, to reduce the need for extracorporeal mem-brane oxygenation (ECMO) in two and to reducethe risk of pneumothorax in one.

Micrograph of microtubules (arrows) in the axon ofa nerve cell. The drawnclock can be objectively scored by a validated scoring system

The drawnclock can be objectively scored by a validated scoring system. In other cases ofspace occupation, MV is safe and often necessary.

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